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. Author manuscript; available in PMC: 2024 Oct 24.
Published in final edited form as: J Fluor Chem. 2023 Feb 21;267:110106. doi: 10.1016/j.jfluchem.2023.110106

Table 3.

Cytotoxicity (IC50 nM) of DFV-fluorotaxoids against 8505C and 8305ATC cell lines [61].

graphic file with name nihms-2029217-t0016.jpg
X R1 R2 IC50 (Mean ± SD)/nM
8505C 8305C
Paclitaxel 5.86 2.51
11a-06 OCHF2 MeCO H 0.57 0.52
11b-05 OCF3 c-PrCO H 1.43 1.15
11d-06 OCHF2 Me2NCO H 1.09 0.36
11e-05 OCHF2 Me H 1.61 0.55
11f-05 OCF3 Me Me 1.41 0.50