Table 2. Logistic regression models by different epigenetic age acceleration measures.

	Model 1a OR [95% CI]	P value	Model 2b OR [95% CI]	P value	Model 3c OR [95% CI]	P value
GrimAA	1.11 [1.03, 1.20]	6.82x10-3	1.13 [1.05, 1.23]	1.58x10-4	1.14 [1.05, 1.25]	2.86x10-3
IEAA	1.10 [1.01, 1.20]	0.02	1.14 [1.04, 1.25]	4.50x10-3	1.13 [1.03, 1.24]	0.01

GrimAA GrimAge acceleration; IEAA Intrinsic epigenetic age acceleration; OR odds ratio; CI confidence interval

^a Model 1 is the univariable logistic regression model between different epigenetic age acceleration measures and BrCa risk.

^b Model 2 is the multivariable logistic regression model including age and self-reported race as covariates.

^c Model 3 is the multivariable logistic regression model including age, self-reported race and other known BrCa risk factors (BMI, age at menarche, parity, smoking status) as covariates.