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. 2024 Aug 29;73(5):1–25. doi: 10.15585/mmwr.rr7305a1

TABLE 4. Dose volumes for inactivated influenza vaccines (IIV3s) approved for children aged 6 through 35 months* — United States, 2024–25 influenza season.

Trade name (Manufacturer) Dose volume for children aged 6 through 35 mos
(μg HA per vaccine virus)
Afluria (Seqirus) 0.25 mL (7.5 μg)
Fluarix (GlaxoSmithKline) 0.5 mL (15 μg)
Flucelvax (Seqirus) 0.5 mL (15 μg)
FluLaval (GlaxoSmithKline) 0.5 mL (15 μg)
Fluzone (Sanofi Pasteur) 0.5 mL (15 μg)§

Abbreviation: HA = hemagglutinin.

* For persons aged ≥36 months (≥3 years), the dose volume is 0.5 mL per dose for all inactivated influenza vaccines.

The approved dose volume for Afluria is 0.25 mL for children aged 6 through 35 months and 0.5 mL for persons aged ≥3 years. However, 0.25-mL prefilled syringes are no longer available. For children aged 6 through 35 months, a 0.25-mL dose must be obtained from a multidose vial.

§ Per the package insert, Fluzone is approved for children aged 6 through 35 months at either 0.25 mL or 0.5 mL per dose; however, 0.25-mL prefilled syringes are no longer available. If a prefilled syringe of Fluzone is used for a child in this age group, the dose volume will be 0.5 mL per dose. The 5.0 mL multidose vials should be accessed for only 10 doses, regardless of the volume of the doses obtained or any remaining volume in the vial. Any vaccine remaining in a vial after the maximum number of doses has been removed should be discarded.