Table 1.

Cellular composition of alveolitis following 3-week exposures of WT and PKD1mKO mice to S. rectivirgula.

	AM (%)	MAC (%)	Neutrophils (%)	CD11c+CD11b-F4/80-(%)	CD11c+CD11b+F4/80-(%)	CD4+ T (%)	CD8+ T (%)
WT	40.63 ± 14.64	3.28 ± 1.03	15.05 ± 7.01	2.20 ± 0.73	1.59 ± 0.27	15.78 ± 5.28	6.14 ± 3.33
PKD1mKO	41.77 ± 5.30	3.87 ± 1.36	15.39 ± 2.91	2.07 ± 0.40	1.80 ± 0.52	13.07 ± 3.52	3.88 ± 1.07

WT (n = 4) and PKD1mKO (n = 5) were exposed to S. rectivirgula (100 μg) three times per week for 3 weeks and analyzed 72 hours after the last exposure. The frequency of alveolar macrophages (AM: CD11c⁺F4/80⁺), macrophages (MAC: CD11b⁺F4/80⁺CD11c^-), neutrophils (CD11b⁺Gr1⁺F4/80^-), CD11c⁺CD11b^-F4/80^- cells, CD11c⁺CD11b⁺F4/80^- cells, CD4⁺ T cells (CD4⁺βTcR⁺), and CD8⁺ T cells (CD8⁺βTcR⁺) in BAL cells were measured by flow cytometry followed by analysis using FlowJo software as described in Materials and Methods and expressed as % of CD45⁺ cells. Values are given as mean ± SD of each group. Gating strategy is shown in Supplementary Figure 3A . Significance was determined by two-tailed Student’s t-test.