Table 3.

Analysis of the association between metastases and EGFR mutations.

EGFR mutations	Metastasis			Lung metastasis			Brain metastasis			Bone metastasis			Live metastasis			Intrapulmonary metastasis			other siters metastasis
	Yes	No	P value	Yes	No	P value	Yes	No	P value	Yes	No	P value	Yes	No	P value	Yes	No	P value	Yes	No	P value
19DEL	187	180	0.332	88	279	<0.001	60	307	0.059	94	273	0.048	24	343	0.842	85	282	0.027	23	344	0.156
L858R	203	218	0.821	67	354	0.149	89	332	<0.001	121	300	0.002	18	403	0.221	70	351	0.962	17	404	0.004
Rare mutations	25	34	0.469	7	52	0.912	12	47	0.061	14	457	0.460	2	57	0.556	8	51	0.536	5	54	0.891
19Del/L858R+ T790M	9	4	0.122	2	11	0.670	3	10	0.195	4	9	0.302	2	11	0.203	3	10	0.469	0	13	0.615
Negative	184	204		48	340		45	343		76	312		24	364		65	323		35	353

P values in bold italic reached statistical significance.