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. 2024 Feb 17;202(12):5531–5544. doi: 10.1007/s12011-024-04093-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — GSPE protects against glucolipotoxicity-induced ferroptosis by activating the Nrf2 pathway. A–H HO-1, NQO1, and Nrf2 expression levels from MIN6 cells determined using western blot and quantified. I, J Immunofluorescence analysis of Nrf2. K Analysis of ARE activity. L–N Cytoplasmic and nuclear Nrf2 proteins detected and quantified using western blot. Data are expressed as mean ± SD (*P < 0.05 vs. control; #P < 0.05 vs. GP)