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Display of conformational and nonconformational epitopes by the GST-COPV L1 and COPV L1 proteins. Equivalent amounts of GST-COPV L1 and COPV L1 (based on L1 content) were tested for immunoreactivity in ELISAs with the conformation-dependent, rabbit polyclonal anti-COPV antiserum (A) and the conformation-independent, mouse anti-AU1 monoclonal antibody (B). Both protein preparations showed similar reactivity with the antibodies.
