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. 2024 Sep 25;16(9):e70147. doi: 10.7759/cureus.70147

Table 1. Characteristic of the included studies.

s-FICB, suprainguinal fascia iliaca compartmental block; PO, per os; IV, intravenous; PCA, patient-controlled analgesia; CR, controlled release; PACU, post-anesthesia care unit; NRS, numerical rating score; VAS, visual analog scale; BD, twice a day; Q6h, every six hours; Q12h, every 12 hours; Q3h, every three hours; Q8h, every eight hours; Q4h, every four hours; OD, once a day; OM, every morning; IM, intramuscular

  Intervention Control Sample size (mean age, year) Intra-operative management Perioperative adjunct therapy
      Intervention Control    
Arthroscopic hip surgery
Behrends et al. (2018) [25] Pre-operative ultrasound-guided s-FICB, ropivacaine 0.2% 40 mL Sham block, normal saline 0.9% 40 mL 38 (35) 40 (32) General anesthesia, IV fentanyl as required. Intra-articular ropivacaine 0.2% 10 mL at the end of surgery IV fentanyl and IV hydromorphone as needed to achieve an NRS ≤ 4 in PACU. Discharged with PO hydrocodone, PO acetaminophen, or PO oxycodone
Glomset et al. (2020) [26]​ Pre-operative ultrasound-guided s-FICB, ropivacaine 0.35% 3 mg/kg (up to 60 mL) with adrenaline 1:400,000 and clonidine 100 μg Intra-articular injection of ropivacaine 0.5% 20 mL 41 (40.6) 43 (36.8) General anesthesia, premedication with PO paracetamol 15 mg/kg, PO celecoxib 400 mg, PO pregabalin 75 mg, PO oxycontin 10 mg, and PO midazolam 1-5 mg. IV fentanyl as required. IV hydromorphone 0.2-0.5 mg (with a maximum dose of 4 mg) in PACU
Huang et al. (2020) [27] Pre-operative ultrasound-guided s-FICB, ropivacaine 0.35% 35-40 mL No block 27 (42.4) 33 (41.4) General anesthesia, premedication with PO pregabalin 150 mg and PO celecoxib 200 mg. Intra-operatively, IV paracetamol 1 g and other analgesia as required. Intra-articular plain bupivacaine 0.5% 10 mL with morphine 10 mg given via arthroscopic ports IV fentanyl/oxycodone as required in PACU. Discharged with oxycodone as required and PO diazepam 5-10 mg for muscle spasm
Hip and femur fracture surgeries
Bang et al. (2016) [28] Post-operative ultrasound-guided s-FICB, ropivacaine 0.2% 40 mL with adrenaline 1:200,000 No block 11 (81) 10 (82) Spinal anesthesia, hyperbaric bupivacaine 0.5% 2 mL with IV ketorolac 30 mg at the end of surgery IV tramadol 25 mg as rescue analgesia in PACU or if the pain was not controlled by PACU. PO celecoxib 200 mg BD and PCA fentanyl at bolus dose 0.5 m μg/kg, a lockout of seven minutes, the four-hour limit of 4 μg/kg
Sahithi et al. (2022) [29] Pre-operative ultrasound-guided s-FICB, ropivacaine 0.5% 30 mL No block 33 (52) 33 (51) Spinal anesthesia, hyperbaric bupivacaine 0.5% with fentanyl 25 μg (volume not documented) IV paracetamol 1 g if VAS > 3, IV tramadol 100 mg if VAS > 6, and IV fentanyl 1 μg/kg If VAS > 6 after paracetamol and tramadol
Dai et al. (2024) [30]​ Post-operative ultrasound-guided s-FICB, ropivacaine 0.33% 30mL No block 31 (76) 31 (74) General anesthesia, IV sufentanil (0.3-0.5 μg/kg), IV lidocaine (1-2 mg/kg), and IV remifentanil titrated to response PO flurbiprofen 1-2 mg/kg and PO tramadol
Total hip arthroplasty
Desmet et al. (2017) [31]​ Pre-operative ultrasound-guided s-FICB, ropivacaine 0.5% 40 mL No block 42 (60.4) 43 (66.5) General anesthesia, IV paracetamol 1 g, IV diclofenac 75 mg, and IV sufentanil boluses as required IV morphine in PACU as required. PCA morphine 1 mg bolus, a lockout of five minutes with four hours of 20 mg, IV paracetamol 1 g Q6h, and IV diclofenac 75 mg Q12h
Gasanova et al. (2019) [32]​​​​​​ Post-operative ultrasound-guided s-FICB, ropivacaine 0.5% 60 mL with adrenaline 1:400,000 and clonidine 100 μg Periarticular injection of 60 mL mixture of ropivacaine 300 mg and adrenaline 150 μg 30 (56.2) 30 (59) General anesthesia, premedication with PO gabapentin 600 mg and PO oxycodone CR 10 mg. Intra-operatively, IV paracetamol 1 g, IV ketorolac 30 mg, and IV fentanyl boluses as required IV hydromorphone 0.1-0.2 mg as required in PACU if VAS > 4, 0.2-0.4 mg Q3h for post-operative day 1 as required. PO meloxicam 15 mg OD, PO gabapentin 300 mg Q8h, PO oxycodone CR 10 mg ON, and PO acetaminophen 1 g Q8h for post-operative day 1 and then changed to PO hydrocodone/acetaminophen 10 mg/325 mg Q4h as required
Gola et al. (2021) [33] Post-operative ultrasound-guided s-FICB, ropivacaine 0.375% 40 mL with adrenaline 1:200,000 No block 50 (65) 50 (65) Spinal anesthesia, 1.7-2.2 mL of hyperbaric bupivacaine 0.5% and premedication with PO paracetamol 500 mg, PO metamizole 500 mg, and PO pregabalin 75 mg PCA oxycodone 1 mg bolus, a lockout of 10 minutes, and PO Oxycodone 10 mg Q12h for post-operative day 1. IV paracetamol 1 g Q6h and IV metamizole 1 g Q6h on post-operative day 1 and then changed to PO paracetamol 1 g Q6h and PO metamizole 1 g Q6h. PO pregabalin 75 mg OM
Carella et al. (2022) [34]​ Pre-operative ultrasound-guided s-FICB, ropivacaine 0.375% 40 mL No block 43 (70) 43 (74) Spinal anesthesia, 2 mL of isobaric bupivacaine 0.5% with sulfentanil 0.2 mL PCA morphine 1 mg bolus, lockout of five minutes with four hours of 20 mg
Demeulenaere et al. (2022) [35]​ Post-operative ultrasound-guided s-FICB, ropivacaine 0.2% 40 mL Control group 1: local infiltration of 150 mL of mixture of ropivacaine 300 mg, ketorolac 30 mg, and adrenaline 1:100,000. Control group 2: no block 49 (68) Control group 1, 50 (68); control group 2, 53 (67) Spinal anesthesia, 2.5 mL of hyperbaric bupivacaine 0.5% IV or PO acetaminophen 1 g Q6h (or reduced to 3 g per 24 hours if with age ≥ 75 years old, weight < 50 kg, liver failure, and chronic ethyl abuse), IM or PO diclofenac 75 mg Q12h, IV tramadol 100 mg, or PO tramadol 50 mg (or reduced to 300 mg per 24 hours if with age ≥ 75 years old, 100 mg per 24 hour if with liver failure, or 200 mg per 24 hours if with kidney failure) as required. IM piritramide 10 mg Q6h as required