Table 1.
Patient characteristics in the study cohort
| SOZ and postoperative seizure outcome | ||
|---|---|---|
| Patient ID and #FR MI network nodes | Intra-cranial EEG SOZ location consensus decision | Outcome |
| IO001 0 nodes FR spike positive | L MT | Engel IA@24 months |
| IO008 27 nodes | L middle temporal gyrus | Engel 1A@48 months |
| IO18 22 Nodes | Right insula, cuneus, inferior and middle frontal gyrus | Engel IA@24months |
| 4122 poor spatial sampling | R inferior temporal gyrus | Engel IA@24 months |
| 4124 4 nodes | R SMA | Engel IA@24 months |
| 4145 32 nodes | L cingulate gyrus, medial frontal gyrus, middle frontal gyrus, superior frontal gyrus | Engel IA@40 months |
| 4166 5 nodes | L MT, uncus, superior temporal gyrus, frontal lesion | Engel IB@42 months |
| IO12 9 nodes | L MT | Engel IIB@24months |
| IO05 41 nodes | R anterior cingulate, MT, uncus | Engel IVB@40 months |
| 453 5 nodes | R MT | Engel IA@60 months |
| 456 incomplete spatial sampling | Bilateral MT, middle temporal gyrus R > L | Engel IVC@48 months |
| 462 11 nodes | L temporal neocortical, L frontal | Engel IV@6 months RNS placed and revised |
| 466 8 nodes | R fusiform gyrus, superior temporal gyrus, uncus | Engel IB@35 months |
| 473 incomplete spatial sampling | L MT, fusiform gyrus, uncus | Engel IIIA@18 months |
| 477 10 nodes | R MT | Engel IB@31 months |
| 479 poor spatial sampling | R insula, bilateral middle temporal gyrus, superior temporal gyrus | Engel IVB@33 months |
| 469 8 nodes | L MT | Engel IIIA@63 months |
| IO21 incomplete spatial sampling | Right orbitofrontal cortex | Engel IVB@24 months |
| 4110 10 nodes | L inferior frontal gyrus, insula, MT | SUDEP @6 weeks |
| IO23 20 nodes | Bilateral MT, right lateral temporal | Engel IVB@24 months |
| IO13 10 nodes | R insula, precuneus, middle occipital gyrus, superior parietal lobule, superior occipital gyrus, superior temporal gyrus, middle temporal gyrus | Engel IIIA@18 months |
| IO15 14 nodes | L MT, R cingulate, post-cingulate, mesial frontal, precuneus | Engel IVB@36 months |
| IO19 23 nodes | R parietal lobe | Engel IVB@36 months |
Poor spatial sampling refers to no electrodes recording FR on spikes at a rate of >1 min, and incomplete spatial sampling refers to the entire FR-generating network resected despite non–seizure-free outcome (see the ‘Materials and methods’ section). The number of nodes in the FR MI network with a LE >0 are listed with the patient ID in the first column.
L, left; R, right; N/A, not applicable; MT, mesial temporal; MTL, mesial temporal lobe; MTS, mesial temporal sclerosis; SMA, supplementary motor area; TBI, traumatic brain injury; LOC, loss of consciousness; RNS, responsive neurostimulator; VNS, vagal nerve stimulator; SUDEP, sudden unexpected death in epilepsy; @, time to last follow-up.