Table I.
DNA-Damaging Agent
|
Sensitivity
|
DNA Damage
|
||||
---|---|---|---|---|---|---|
rev1 | rev7 | rev1rev3 | rev3a | |||
Short-term UV-B | Light | + | − | ++ | ++ | |
Dark | ± | − | + | + | CPD, 6-4PP, etc. | |
Long-term UV-B | + | + | n.t. | + | ||
Cisplatin | ± | ± | + | + | DNA crosslink, alkylation, etc. | |
γ-Rays | − | − | + | + | DSB, base damage, etc. |
Sakamoto et al. (2003) and this study.