Table 1.

Current clinical cases of therapeutic application of mycobacteriophages.

Infection	Number of Cases	Type of Infection	Underlying Condition	Monophage\Cocktail (Number of Cases)	Administration Route	Antibiotic Combination	Outcome (Number of Cases)	Ref.
M. abscessus subsp. abscessus	12	Disseminated, lung	CF, lung transplant	Monophage (6), Cocktail (6)	Intravenous, aerosol, bronchoscopic administration	At least 2 drugs for patient	Positive (6), inconclusive responses (2), no response to therapy (4)	[64,65]
M. abscessus subsp. massiliense	5	Disseminated, lung, sternal bone infection	CF, lung transplant, scleroderma, chronic lung bronchiectasis	Monophage (3), Cocktail (2)	Intravenous, aerosol, topical, chest wash	At least 2 drugs for patient	Positive (2), inconclusive responses (3)	[65,66,67,68]
M. chelonae	1	Cutaneous	Seronegative arthritis on immunosuppression	Monophage	Intravenous	Omadacycline, Bedaquiline, and Trimethoprim-sulfamethoxazole	Positive	[65,69]
M. avium complex	1	Lung	CF	Monophage	Intravenous, aerosol	At least 2 drugs for patient	Positive	[65]
BCG	1	Disseminated	Mendelian susceptibility to mycobacterial disease, heterozygous mutation in NFKBIA gene	Cocktail	Intravenous	At least 2 drugs for patient	Positive	[65]