Table 2.
Clinical characteristics of the study cohort (657 patients).
| Sex (%) | F | 521 (79.3) |
| M | 136 (20.7) | |
| Age (median, IQR) | 46.8 [38.3, 55.8] | |
| cN+ (central compartment) (%) | No | 605 (92.1) |
| Yes | 52 (7.9) | |
| Type of surgery (%) | Thyroid lobectomy | 218 (33.2) |
| Total thyroidectomy | 439 (66.8) | |
| pT 8th Ed AJCC (%) | 1a | 279 (42.5) |
| 1b | 247 (37.6) | |
| 2 | 93 (14.2) | |
| 3a | 23 (3.5) | |
| 3b | 15 (2.3) | |
| Microcarcinoma (%) | No | 446 (67.9) |
| Yes | 211 (32.1) | |
| Central neck dissection (%) | Monolateral | 423 (64.4) |
| Bilateral | 234 (35.6) | |
| Multifocality (%) | No | 461 (70.2) |
| Yes | 196 (29.8) | |
| Type of multifocality (%) | Multi one lobe | 88 (44.9) |
| Single each lobe | 52 (26.5) | |
| Multi each lobe | 56 (28.6) | |
| pN (%) | N0 | 417 (63.5) |
| N1a | 240 (36.5) | |
| Extranodal extension (% on pN+) | No | 199 (82.9) |
| Yes | 41 (17.1) | |
| Total nodes in the dissection (median, IQR) | 6.00 [3.00, 9.00] | |
| Node micromestasis | Yes | 64 (26.6) |
| Complication (%) | No | 371 (56.5) |
| Yes | 286 (43.5) | |
| Recurrent nerve section (%) | No | 656 (99.8) |
| Yes | 1 (0.2) | |
| Temporary vocal fold palsy (%) | No | 573 (87.2) |
| Yes | 84 (12.8) | |
| Permanent vocal fold palsy (%) | No | 645 98.2) |
| Yes | 12 (1.8) | |
| Temporary hypocalcemia (%) | No | 380 (57.8) |
| Yes | 277 (42.2) | |
| Permanent hypocalcemia (%) | No | 576 (88.1) |
| Yes | 78 (11.9) | |
| Completion thyroidectomy (%) | No | 603 (91.8) |
| Yes | 54 (8.2) | |
| Radioactive iodine (RAI) therapy (%) | No | 350 (53.3) |
| Yes | 307 (46.7) | |
| RAI for pN+ (%) | No | 465 (70.7) |
| Only for N | 99 (15.1) | |
| N + other factors | 93 (14.2) | |
| Recurrence (%) | No | 639 (97.3) |
| Yes | 18 (2.7) | |
| State of disease (%) | NED | 636 (96.8) |
| AWD | 4 (0.6) | |
| DOC | 16 (2.4) | |
| DOD | 1 (0.0) | |
| Follow-up, months (median, IQR) | 75 [48, 114] |
Legend: AJCC American Joint Committee on Cancer, IQR interquartile range.