Table 4.

Cox proportional hazard models (univariable and multivariable).

Univariable Models
Variables	DFS
	HR	CI 95%	p-Value
Sex
▪F	1
▪M	1.42	0.66–3.04	0.369
Age categorized
▪≤55 years	1
▪>55 years	2.93	1.49–5.75	0.002
pT			<0.001
▪T1	1
▪T2	1.65	0.66–4.11	0.284
▪T3a	10.10	4.01–25.43	<0.001
▪T3b	2.78	0.64–12.01	0.172
Multifocality
▪No	1
▪Yes	0.67	0.30–1.48	0.320
Macroscopic extracapsular extension
▪No	1
▪Yes	2.93	0.70–12.27	0.141
pN
▪N0	1
▪N1a	1.10	0.55–2.19	0.783
Extranodal extension
▪No	1
▪Yes	3.24	1.33–7.91	0.010
Multivariable Models
Variables	DFS
	HR	CI 95%	p-Value
Age categorized
▪≤55 y	1
▪>55 y	3.06	1.51–6.20	0.002
pT			<0.001
▪T1	1
▪T2	1.58	0.63–3.94	0.329
▪T3a	7.14	2.76–18.48	<0.001
▪T3b	2.08	0.48–9.42	0.343
Extranodal extension
▪No	1
▪Yes	3.10	1.18–8.14	0.021

Legend: DFS = disease-free survival, HR = hazard ratio, CI = confidence interval. Bold indicates results with significant impact.