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. 2024 Sep 27;12(10):2207. doi: 10.3390/biomedicines12102207

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The expression pattern of TIGIT on NK cells of CBF-AML patients at diagnosis and HDs. (a) the representative histogram of TIGIT expression on CD56^dim NK cells of HD. (b) the representative histogram of TIGIT expression on CD56^bright NK cells of HD. (c) the expression pattern of TIGIT on NK cells between CBF-AML patients at diagnosis and HDs. (d) the expression pattern of TIGIT on NK cells between CBF-AML patients at diagnosis and HDs after stimulation in vitro. (e) the frequencies of TIGIT⁺ NK cells of CBF-AML patients before and after stimulation in vitro. (f) the frequencies of TIGIT⁺ NK cells of HDs before and after stimulation in vitro. CBF-AML: core binding factor-acute myeloid leukemia, HDs: healthy donors, MFI: mean fluorescence intensity. Numbers in this figure refer to the p values.