Table 1.

The CCCD’s experimental RSM results for the MAE optimization of the independent variables’ (X₁, X₂, and X₃) assessed responses (Yield, TPC, DPPH, ABTS, and BCM). Variables are presented in natural values and codified ranges.

	Experimental Design						Responses
	Coded Values			Natural Values
	X 1	X 2	X 3	X 1 : t	X 2 : P	X 3 : S	Y	TPC	DPPH •	ABTS	BCM
				min	Bar	%	mg/g dw	mg FE/g dw	nM R·/g dw	nM R·/g dw	µM βC/g dw
1	−1	−1	−1	7.5	5.6	20.3	426.77	57.12	32.70	41.73	0.0902
2	−1	−1	1	7.5	5.6	79.7	330.76	46.50	32.12	159.51	0.1037
3	−1	1	−1	7.5	16.4	20.3	514.74	69.46	39.99	44.61	0.1060
4	−1	1	1	7.5	16.4	79.7	362.82	52.28	34.79	280.31	0.0354
5	1	−1	−1	20.5	5.6	20.3	541.44	61.89	42.05	53.86	0.1279
6	1	−1	1	20.5	5.6	79.7	370.05	52.19	29.83	56.22	0.0481
7	1	1	−1	20.5	16.4	20.3	462.27	61.70	41.84	29.30	0.0913
8	1	1	1	20.5	16.4	79.7	326.94	48.42	26.19	184.17	0.0712
9	1.68	0	0	25	11	50	423.36	58.72	32.49	168.26	0.0806
10	−1.68	0	0	3	11	50	339.81	64.29	44.94	165.00	0.0870
11	0	−1.68	0	14	2	50	323.71	44.04	30.59	84.13	0.0950
12	0	1.68	0	14	20	50	457.90	63.23	38.15	85.67	0.0757
13	0	0	−1.68	14	11	0	452.43	43.58	26.07	180.96	0.0959
14	0	0	1.68	14	11	100	100.33	19.23	13.25	22.51	0.0017
15	−1.68	−1.68	−1.68	3	2	0	283.57	24.48	12.20	216.08	0.0677
16	−1.68	−1.68	1.68	3	2	100	59.64	6.07	2.22	4.46	0.0017
17	−1.68	1.68	−1.68	3	20	0	393.25	33.17	17.52	18.40	0.0781
18	−1.68	1.68	1.68	3	20	100	115.62	16.39	11.76	19.92	0.0046
19	1.68	−1.68	−1.68	25	2	0	345.64	31.39	16.46	181.43	0.1029
20	1.68	−1.68	1.68	25	2	100	55.48	2.93	1.46	2.70	0.0017
21	1.68	1.68	−1.68	25	20	0	365.07	32.35	17.77	36.29	0.0391
22	1.68	1.68	1.68	25	20	100	112.57	11.38	14.17	36.33	0.0096
23	0	0	0	14	11	50	385.65	62.49	33.79	169.41	0.0946
24	0	0	0	14	11	50	371.11	69.10	32.96	195.22	0.0950
25	0	0	0	14	11	50	411.94	62.68	27.71	199.82	0.0908
26	0	0	0	14	11	50	369.34	62.99	30.63	119.88	0.0926
27	0	0	0	14	11	50	400.93	59.00	23.27	180.36	0.1029
28	0	0	0	14	11	50	380.33	48.41	23.03	183.10	0.0959