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. 2024 Oct 17;13(10):1250. doi: 10.3390/antiox13101250

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of aged-to-young FMT on vascular and systemic inflammation, and vascular telomere function. (A) RT-PCR on mRNA levels of pro-inflammatory genes in aortas of Aged, young-transplanted (Young (Control)) and aged-transplanted mice (Young (FMT)). (B) ELISA on circulating inflammatory markers of different mouse groups. (C) ELISA on circulating GLP-1 levels of different mouse groups. (D) Tert mRNA level in aortas of different mouse groups. (E) Telomerase activities in aortas of different mouse groups. (F) Relative telomere length in aortas of different mouse groups. N = 8 per group. Data are mean ± SD. * p < 0.05; Brown-Forsythe and Welch ANOVA and Dunnett T3 test.