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. 2024 Oct 17;13(10):1250. doi: 10.3390/antiox13101250

Figure 4.

Figure 4

Effects of aged-to-young FMT on intestinal inflammation, telomere function and barrier function. (A) RT-PCR on mRNA levels of pro-inflammatory genes in intestines of Aged, young-transplanted (Young (Control)) and aged-transplanted mice (Young (FMT)). (B) Lucigenin-enhanced chemiluminescence on intestinal ROS levels of different mouse groups. (C) Tert mRNA level in intestines of different mouse groups. (D) Telomerase activities in intestines of different mouse groups. (E) Relative telomere length in intestines of different mouse groups. Endotoxin levels in (F) feces and (G) sera of different mouse groups. ELISA on serum levels of (H) LBP and (I) I-FABP of different mouse groups. (J) Proglucagon mRNA level in intestines of different mouse groups. N = 8 per group. (K) Representative Western blots and quantification of Western blotting on expression of AMPK and p-AMPK at Thr172 in intestines of different mouse groups. N = 6 per group. Data are mean ± SD. * p < 0.05; Brown-Forsythe and Welch ANOVA and Dunnett T3 test.