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. 2024 Oct 15;13(10):1240. doi: 10.3390/antiox13101240

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) In situ antioxidant activity of ascorbic acid (AA), fullerene (C60), natural fullerene (NC60), and Pluronic F127-coated NC60 nanoaggregates (NC60/PF127) via beta-carotene assay. In vitro cytotoxicity and antioxidant activity of Pluronic F127-coated NC60 (NC60/PF127) in CCK-8 and H₂DCFDA assay. (B) Cell viability and (C) intracellular ROS level after treatment with NC60/PF127 (1:5). Negative control (Neg) and positive control (Pos) groups indicate the lowest and highest ROS levels, respectively (* p < 0.05).