FIG. 8.

Relative readthrough activity of HPV-31 wild-type and mutant polyadenylation signals in the context of the complete genome within differentiated NHKs. The ratio of E4∧L1- to E1∧E4-containing transcripts, or readthrough activity, is presented relative to the wild-type lines. The generation of stable lines was repeated twice using two different foreskin donors, NHK.1 and NHK.2, to ensure reproducibility.