Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Oct 21;13(20):1744. doi: 10.3390/cells13201744

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Integrated analysis of RNA-Seq and MeRIP-Seq. (A) Venn diagram depicting peak numbers with differential m⁶A methylation and changes in mRNA expression. (B) Four-quadrant plot illustrating the distribution of genes. Different colors indicate different changes in RNA expressions or m⁶A methylation levels. (C) Heatmap displaying the expression of 27 genes with notable differences in methylation levels. (D) MeRIP-qPCR validation of 5 m⁶A-methylated genes, using IgG as a negative control. (E) qPCR analysis showing increased expression of 5 hyper-up genes in LW pigs compared with NX pigs. (F) IGV visualisation of RNA-seq (grey) data and MeRIP-seq (red and blue) data at the SH3BP4 gene loci. * p < 0.05, ** p < 0.01.