Figure 2.
Effect of KGC01CE on DEX-induced muscle atrophy in the C2C12 models. (A) Representative image of muscle atrophy. (B) Myotube diameter. After pre-treatment with 50 μg/mL of individual extracts or a ratio-based mixture in differentiated myotubes, 100 μm DEX treatment was administered for 24 h. Subsequently, the images were captured using a microscope, and the myotube diameter was measured using the ImageJ software. NC: negative control (untreated), C:DEX, Ce: Ce + DEX, Eu: Eu+ DEX, CE(3:1): Ce:Eu (3:1)+ DEX, CE(1:1): Ce:Eu (1:1) + DEX, CE(1:3): Ce:Eu (1:3) + DEX. Data are expressed as mean ± SD. *** p< 0.001, n.s: not significant, scale bar = 50 μm.
