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. 2024 Oct 4;46(10):11190–11206. doi: 10.3390/cimb46100664

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of KGC01CE on body weight and food intake in aged rats. (A) Experimental design, (B) body weight, and (C) food intake (g/day). Fifteen-month-old male rats were orally administered with KGC01CE at concentrations of 50, 100, and 200 mg/kg for 12 weeks. NC: young SD rats, C: aged SD rats, KGC01CE − 50:aged SD rats + CE(1:3) 50 mg/kg b.w, KGC01CE − 100:aged SD rats +CE(1:3) 100 mg/kg b.w, KGC01CE − 200: aged SD rats +CE(1:3) 200 mg/kg b.w. Data are expressed as mean ± SD (n = 6). ** p < 0.01, *** p < 0.001, n.s: not significant.