Table 4.
Plasma measurements following chronic 4V infusions of OT (16 nmol/day) or vehicle in female HFD-fed C57BL/6J mice. Data are expressed as mean ± SEM (N = 7–10/group).
| 4V Treatment | Vehicle | OT |
|---|---|---|
| Leptin (ng/mL) | 10.0 ± 1.3 a | 6.7 ± 1.3 a |
| Insulin (ng/mL) | 0.5 ± 0.1 a | 0.3 ± 0.04 a |
| Glucagon (pmol/L) | 23.3 ± 3.7 a | 34.1 ± 13.2 a |
| FGF-21 (pg/mL) | 467.5 ± 129.7 a | 513.6 ± 179.6 a |
| Irisin (mg/mL) | 4.1 ± 0.2 a | 3.9 ± 0.2 a |
| Adiponectin (mg/mL) | 19.3 ± 1.0 a | 20.1 ± 1.8 a |
| Blood Glucose (mg/dL) | 155 ± 2.7 a | 152.6 ± 8.5 a |
| FFA (mEq/L) | 0.13 ± 0.01 a | 0.11 ± 0.01 a |
| Total Cholesterol (mg/dL) | 105.9 ± 2.9 a | 95.3 ± 9.5 a |
Blood was collected by tail vein nick (blood glucose) or from the trunk following a 6-h fast. Different letters denote significant differences between treatments. Shared letters are not significantly different from one another.