FIG. 1.
Schema of cosmid mutations. The upper section depicts the VZV IR-US-TR region of the genome containing the coding regions of ORFs 62 to 71, and the unique AvrII site in the US region is indicated. The lower section is an expanded view of the region between ORFs 70 and 63. The nucleotide numbers of the start and stop sites of the ORFs that were deleted (ORFs 63, 64, 69 and 70), as well as the nucleotide numbers of the relevant adjacent ORFs, are given. The designations of the various cosmids generated are shown on the left. Hatched boxes, deleted ORFs.