Figure 1.

Definitions of remission after biologic therapy using strict and relaxed domain cutoffs. *Prednisolone equivalent; ^†Control was assessed by Global Initiative for Asthma control criteria, Asthma Control Questionnaire, or Asthma Control Test; ^‡Post-bronchodilator used if available, and prebronchodilator used otherwise, while ensuring that pre- and postbiologic measures were both either pre- or post-bronchodilator. Post-bronchodilator measurements were used for 61.6% of patients with available prebiologic percent predicted FEV₁ (ppFEV₁) (n = 2,705). The remaining 38.4% of patients were all treated with inhaled corticosteroid/long-acting β₂-agonist (i.e., bronchodilator not specifically withheld). LTOCS = long-term oral corticosteroid.