Table 5.
Plasma lipid profile and HDL particle composition of RA groups according to the disease activity.
| Remission/Low-Activity Disease DAS28 < 3.2 (n = 13) |
Active Disease DAS28 ≥ 3.2 (n = 43) |
p | |
|---|---|---|---|
| TC (mg/dL) | 192 (177–211) | 194 (169–204) | 0.719 |
| HDLc (mg/dL) | 60 (51–75) | 50 (43–60) | 0.021 |
| LDLc (mg/dL) | 109 (100–132) | 122 (96–126) | 0.662 |
| apoB (mg/dL) | 34 (28–37) | 35 (30–41) | 0.196 |
| non-HDLc (mg/dL) | 121 (115–146) | 140 (120–149) | 0.221 |
| TG (mg/dL) | 80 (56–88) | 104 (77–135) | 0.007 |
| TG/HDLc | 1.1 (0.9–1.7) | 1.9 (1.5–3.2) | 0.003 |
| TC/apoB | 5.8 (5.4–6.7) | 5.3 (4.9–5.8) | 0.014 |
| HDL particle composition | |||
| HDL-TC (mg/dL) | 54 (47–68) | 44 (34–51) | 0.005 |
| HDL-TG (mg/dL) | 7 (6–12) | 9 (6–11) | 0.696 |
| HDL-PL (mg/dL) | 108 (90–128) | 99 (79–116) | 0.114 |
| HDL-apoA-1 (mg/dL) | 61 (47–69) | 49 (39–58) | 0.014 |
RA: rheumatoid arthritis group; TC: total cholesterol; HDLc: HDL cholesterol; LDLc: LDL cholesterol; TG: triglyceride; apoB: apolipoprotein B; HDL-TC: total cholesterol in HDL; HDL-TG: triglycerides in HDL; HDL-PL: phospholipids in HDL; HDL-apoA-1: apolipoprotein A-1 in HDL. Results are expressed as median and interquartile intervals (25% and 75%). Data were compared using the Mann–Whitney test, always as two-sided analyses.