Figure 2.

Diagrammatic representation of one generic cell showing how different natural molecules could inhibit multiple targets of SARS-CoV-2. Luteolin and eriodictyol would inhibit both ACE2 and TLR4, while oleuropein, hydroxytyrosol, and sulforaphane would inhibit the serine esterases and RNA polymerases, as well as the mammalian target of rapamycin (mTOR) and the inflammasome. Black arrows indicate activation, green T lines indicate inhibition, blue arrows indicate outcomes, and red arrows indicate secretion extracellularly.