Table 3.
Correlations of HMGB1, TGF-β1, BIRC3, ADAM17, CDKN1A, and FTO relative mRNA expression with the change in left ventricular structure and function echocardiographic parameters within the six-month follow-up after myocardial infarction.
LV Parameter Change (∆) | 2−ΔCt HMGB1 | 2−ΔCt TGFβ | 2−ΔCt BIRC3 | 2−ΔCt ADAM17 | 2−ΔCt CDKN1A | 2−ΔCt FTO | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
R | p | R | p | R | p | R | p | R | p | R | p | |
∆ LVEDD, mm | 0.26 | 0.01 | 0.21 | 0.05 | 0.08 | 0.43 | 0.1 | 0.32 | 0.2 | 0.06 | 0.23 | 0.03 |
∆ LVESD, mm | 0.07 | 0.5 | 0.09 | 0.42 | 0.2 | 0.06 | 0.04 | 0.72 | 0.06 | 0.59 | 0.14 | 0.19 |
∆ LVEF, % | −0.13 | 0.22 | −0.13 | 0.23 | −0.16 | 0.12 | 0.03 | 0.73 | 0.07 | 0.48 | −0.02 | 0.87 |
∆ LVEDVi, mL/m2 | 0.25 | 0.02 | 0.18 | 0.09 | −0.18 | 0.08 | 0.02 | 0.85 | 0.06 | 0.58 | 0.02 | 0.84 |
∆ LVESVi, mL/m2 | 0.23 | 0.03 | 0.19 | 0.07 | −0.02 | 0.84 | 0.01 | 0.88 | 0.02 | 0.86 | 0.02 | 0.81 |
∆ SV, mL | 0.21 | 0.05 | 0.2 | 0.06 | −0.01 | 0.94 | 0.44 | 0.67 | 0.06 | 0.58 | 0.04 | 0.67 |
∆ LVMi, g/m2 | 0.22 | 0.05 | 0.18 | 0.1 | −0.05 | 0.63 | 0.19 | 0.08 | 0.11 | 0.31 | 0.1 | 0.35 |
∆ GLS, % | −0.11 | 0.28 | 0.001 | 0.99 | 0.27 | 0.01 | −0.02 | 0.84 | −0.01 | 0.92 | −0.03 | 0.74 |
Values are presented as Spearman’s correlation coefficient (R) and p value of the correlation. p < 0.05 was considered statistically significant. GLS—global longitudinal strain.