Figure 8.

Effects of 22A1 overexpression on promastigotes’ sensitivity to sterol synthesis inhibitors. Log-phase promastigotes were inoculated in various concentrations of ketoconazole (A), posaconazole (B) or DB766 (C). Cell densities were determined after 48 h, and percentages of growth were calculated using cells grown in the absence of inhibitors as controls. Error bars represent standard deviations from three experiments.