FIG. 3.

Secretion of β-chemokines (A) and other cytokines (B) of CD8⁺ T cells of HIV-1-seronegative individuals (open squares), asymptomatic HIV-1-seropositive individuals (gray squares), and CTL clones (black squares). Supernatants of CD3-stimulated CD8⁺ T cells were collected after 0, 4, and 16 h; time zero denotes supernatant of 4-h incubation without anti-CD3 stimulation. Supernatants were tested for cytokine concentrations by ELISA (see Materials and Methods). The asterisks indicate a statistically significant difference of cells from seronegative individuals against both cells from seropositive individuals and CTL clones (P < 0.05; Fisher's exact test). All error bars for at least five independent experiments are calculated, but some are too small to show.