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. 2024 Sep 30;10(10):636. doi: 10.3390/gels10100636

Table 2.

Applications of essential oils incorporated in hydrogels.

Method of Preparations Materials Encapsulated Essential Oils Applications References
Biomedical applications Physical crosslinking Sodium alginate/Fucoidan Menthol, L-linalool, bergamot oil, and β-pinene Topical or transdermal administration [43]
Physical crosslinking Methylcellulose (10% (w/v)) Melissa officinalis EO Treatment of oral candidiasis. [44]
Chemical crosslinking Polyvinyl Alcohol/Corn Starch Hydrogel Films loaded with Silver Nanoparticles Patchouli EO Antimicrobial materials (against Staphylococcus aureus and Staphylococcus epidermidis) [45]
Solvent displacement method Poly-(D,L)-(lactic-co-glycolic acid) Thyme EO Inflammatory skin disorders [47]
Physical crosslinking Polyvinyl alcohol/kaolin Cedar EO Wound dressing [49]
Covalent and physical crosslinking Chitosan/oxidized pullulan Clove EO Wound dressings [52]
Cold gelation process Polymeric-Micelles-Based Hydrogels (Pluronic F127–20%w/w; and Pluronic L 31—1%w/w) Oregano EO Cutaneous application [57]
Chemical crosslinking; casting method Polyvinyl alcohol/polyvinyl pyrrolidone; hydroxypropyl methyl cellulose; sodium alginate; polyethylene glycol; glycerol; Zn stearate; vitamin A and E Fennel, pine, mint and thyme EO Wound dressings [63]
Chemical crosslinking Ultrasound-assisted deacetylated chitosan/ρ-coumaric acid Clove EO Chemotherapeutic/chemopreventive agent [75]
Thin-film dispersion technique/heat-induced gelation. Pea protein (30%) and gum Arabic (1.5%); Soybean lecithin; maltodextrin and gum Arabic Thyme EO Delivery of bioactive compounds (food packing material, tissue engineering or drug delivery) [79]
Physical crosslinking Carboxymethyl chitosan/carbomer 940 Eucalyptus, ginger, and cumin EO Burn dressing material for skin burn repair [86]
Dental applications Physical crosslinking Xanthan gum/Glycerin/Lyophilized Whey/Polyvinylpyrrolidone/PEG 400 Oregano®, Frankincense®, Thieves®, Frankincense® EO Therapy of periodontitis [94]
Cosmetics applications Ionic gelation Poly(vinyl alcohol), silk sericin, and gelatin/chitosan nanoparticles Camellia oleifera EO Cosmetic product (facial masks) [104]
Food applications Emulsification/ionic crosslinking Pectin and pectin/chitosan hydrogel beads Green and roasted coffee EO Systems for the delivery and controlled release of essential oils; food applications [111]
Food packaging applications Gelation/casting Sodium alginate/acacia gum Cinnamon EO Hydrogel-based films as active food packaging materials [129]
Restorations of the stone cultural heritage Preparation directly in situ Sodium alginate Thyme EO Biocides for restoration in a real case of study, i.e., the mosaic Le Professioni e le Arti of Fortunato Depero [146]