Table 5.
The genes related to the immune system that have an RSW-specific mutation in the gene region (±10 kb from the gene boundaries).
| Number of RSW-Specific Mutations ±10 kb of Gene | Description | Gene |
|---|---|---|
| 16 | MHC class II M beta chain 1 | DMB1 |
| 8 | Major histocompatibility complex class II beta chain BLB1 | BLB1 |
| 2 | class II histocompatibility antigen, B-L beta chain | MHCY2B2 |
| 16 | major histocompatibility complex, class II, DM beta 2 | DMB2 |
| 17 | B locus M alpha chain 1 precursor | DMA |
| 19 | beta-2-microglobulin precursor | B2M |
| 15 | uncharacterized protein LOC101747454 precursor | BLB2 |
| 5 | antigen peptide transporter 1 | TAP1 |
| 14 | T-cell surface glycoprotein CD1B precursor | CD1B |
| 11 | tapasin isoform 1 precursor | TAPBP |
| 2 | protein disulfide-isomerase A3 precursor | PDIA3 |
| 1 | ADP-ribosylation factor-like protein 8B | ARL8B |
| 6 | TNF receptor-associated factor 6 | TRAF6 |
| 8 | major facilitator superfamily domain-containing protein 6 | MFSD6 |
| 11 | telomere-associated protein RIF1 | RIF1 |
| 21 | complement component C6 | C6 |
| 5 | interleukin-2 receptor subunit beta precursor | IL2RB |
| 31 | protein kinase C delta type | PRKCD |
| 12 | complement component C8 alpha chain | C8A |
| 1 | tyrosine-protein phosphatase nonreceptor type 6 | PTPN6 |
| 7 | Sushi, von Willebrand factor type A, EGF, and pentraxin domain-containing protein 1 | CR1 |
| 4 | C-C chemokine receptor type 6 | CCR6 |
| 77 | B-cell lymphoma 6 protein homolog | BCL6 |
| 12 | transferrin receptor protein 1 | TFRC |
| 8 | complement component C7 precursor | C7 |
| 2 | interleukin-21 receptor | IL21R |
| 13 | 60 kDa heat shock protein, mitochondrial precursor | HSPD1 |
| 1 | DNA mismatch repair protein MLH1 | MLH1 |
| 5 | complement C2 | C2 |
| 8 | CD81 antigen | CD81 |
| 1 | uracil-DNA glycosylase | UNG |
| 1 | HLA class II histocompatibility antigen gamma chain | CD74 |
| 1 | C-C chemokine receptor type 7 | CCR7 |
| 5 | nucleotide-binding oligomerization domain-containing protein 1 | NOD1 |
| 22 | ras-related protein RAB3C | RAB3C |
| 13 | autophagy protein 5 | ATG5 |
| 10 | WD repeat- and FYVE domain-containing protein 4 | WDFY4 |
| 14 | T-cell surface glycoprotein CD1B precursor | CD1B |
| 2 | protein disulfide-isomerase A3 precursor | PDIA3 |
| 11 | telomere-associated protein RIF1 | RIF1 |
| 6 | netrin-1 precursor | NTN1 |
| 12 | complement component C8 alpha chain | C8A |
| 4 | C-C chemokine receptor type 6 | CCR6 |
| 2 | interleukin-6 precursor | IL6 |
| 2 | interleukin-21 precursor | IL21 |
| 4 | tyrosine-protein kinase SYK | SYK |
| 2 | DNA mismatch repair protein MSH6 | MSH6 |
| 1 | tumor necrosis factor receptor superfamily member 13B | TNFRSF13B |
| 1 | toll-like receptor 4 precursor | TLR4 |
| 70 | SAM domain-containing protein SAMSN1 | SAMSN1 |
| 4 | nuclear factor of activated T cells, cytoplasmic 2 | NFATC2 |
| 14 | mRNA decay activator protein ZFP36L1 | ZFP36L1 |
| 1 | cytotoxic T-lymphocyte protein 4 precursor | CTLA4 |
| 8 | apoptosis regulator BCL2 | BCL2 |
| 26 | serine/threonine-protein phosphatase 2A regulatory subunit B″ subunit gamma | PPP2R3C |