Table 1. Baseline characteristics of study population.
| Pooled Cohort (N = 13,863) |
KPSC (N = 307,931) |
|
|---|---|---|
| Age, years | 60.7 (7.8) | 54.8 (9.0) |
| Year of enrollment | 2000–2007 | 2009 |
| Sex | ||
| Female | 8,117 (58.6%) | 182,515 (59.3%) |
| Male | 5,746 (41.4%) | 125,416 (40.7%) |
| Race | ||
| Non-Hispanic Black | 5,356 (38.6%) | 60,423 (19.6%) |
| Non-Hispanic White | 8,507 (61.4%) | 247,508 (80.4%) |
| Smoking status | ||
| Never | 6,669 (48.1%) | 211,670 (68.7%) |
| Former | 5,048 (36.4%) | 73,918 (24.0%) |
| Current | 2,110 (15.2%) | 22,343 (7.3%) |
| Body mass index, kg/m2 | 28.6 (5.9) | 29.0 (6.3) |
| Lipids, mg/dL | ||
| Total cholesterol | 200 (31) | 203 (32) |
| HDL cholesterol | 54 (17) | 55 (15) |
| LDL cholesterol | 123 (27) | 124 (26) |
| Triglycerides | 102 (75, 143) | 102 (74, 145) |
| Blood pressure, mm Hg | ||
| Systolic | 125 (17) | 124 (14) |
| Diastolic | 76 (10) | 74 (10) |
| hsCRP, mg/L | 2.1 (0.9, 4.7) | 2.0 (0.8, 5.1) |
| Anti-hypertensive medication use | 4,698 (33.9%) | 104,291 (33.9%) |
| Female conditions | ||
| Gestational diabetes | 25 (0.3%) | 2,153 (1.2%) |
| Gestational hypertension | 53 (0.7%) | 946 (0.5%) |
| Preeclampsia | NA | 1,916 (1.0%) |
| Premature menopause | 1,248 (15.4%) | 246 (0.1%) |
* Values are mean (SD), median (25th, 75th percentile), or number (%).
HDL: high-density lipoprotein; hsCRP: high-sensitivity C-reactive protein; KPSC: Kaiser Permanente Southern California; LDL: low-density lipoprotein; NA: not available.