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. 2024 Oct 17;25(20):11185. doi: 10.3390/ijms252011185

Figure 1.

Figure 1

Illustration depicting the characteristics of stem cells (SCs), cancer cells (CCs), and CSCs. The transformation of SCs into CCs and CSCs is influenced by various factors and conditions, which subsequently support cancer cell self-renewal and tumor recurrence. This image highlights associations of CCs and CSCs with various processes, such as stress, chemo and radiation therapy, and metabolic reprogramming, which contribute to CC progression, CSC self-renewal, and metastasis.