Table 3.
Cutoff, sensitivity, specificity, and positive and negative predictive values (% and 95% confidence intervals) of clinical variables for confirmed primary aldosteronism.
| Cutoff Value | Sensitivity % (95% CI) | Specificity % (95% CI) | Predictive Value | Overall Accuracy 1 (%) | ROC (95% CI) | N | ||
|---|---|---|---|---|---|---|---|---|
| Positive % (95% CI) | Negative % (95% CI) | |||||||
| Aldosterone (ng/dL) | ≥16.95 | 84.8 (80.0–88.8) |
83.4 (82.1–84.7) |
30.7 (27.4–34.1) |
98.4 (97.9–98.9) |
8.5 | 0.920 (0.908–0.933) |
3464 |
| A/PRA | ≥29.88 | 96.2 (91.4–98.8) |
90.1 (88.8–91.3) |
35.9 (30.9–41.1) |
99.8 (99.4–99.9) |
90.4 | 0.963 (0.942–0.984) |
2414 |
| A/PRC | ≥2.44 | 99.3 (96.2–100.0) |
92.9 (91.1–94.5) |
69.2 (62.5–75.4) |
99.9 (9.3–100.0) |
93.8 | 0.984 (0.978–0.990) |
1050 |
1 Overall accuracy = percentage of correct classification.