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Effect of Stat3 inhibitor on the expression of LIF-regulated genes in vivo. Mice were given intrauterine injections of PBS (control) in one horn and Stat3 peptide inhibitor in the other on day 3 of pregnancy. LE was isolated on day 4 (1600 hours), and total RNA was extracted. The expression levels of LIF-regulated genes were determined by real-time PCR. The mean reduction compared with control between paired treatments (n = 10) is indicated as a percentage.
