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. 2005 Jun 3;102(24):8495–8500. doi: 10.1073/pnas.0503244102

Fig. 5.

Fig. 5.

An abbreviated biosynthetic pathway leading from l-tyrosine to morphine showing the initial isoquinoline alkaloid, (S)-norlaudanosoline, the change of configuration from (S)- to (R)-reticuline and the bifurcate pathway from thebaine to morphine.