Table 2.
Cases (N = 292) |
Controls (N = 281) |
χ2 * | p | p adj ** | ||
---|---|---|---|---|---|---|
ASTN1 rs146756455 G/C | ||||||
genotype | GG | 277 (95.85) | 264 (95.31) | 1.23 | 0.542 | 3.276 |
GC | 11 (3.81) | 13 (4.69) | ||||
AC | 1 (0.34) | 0 | ||||
allele | G | 564 (97.58) | 538 (97.11) | 0.24 | 0.626 | 2.136 |
A | 14 (2.42) | 16 (2.89) | ||||
EBF1 SNP rs2963463 T/C | ||||||
genotype | TT | 25 (8.68) | 17 (6.09) | 10.47 | 0.005 | 0.030 |
TC | 156 (54.1) | 121 (43.37) | ||||
CC | 107 (37.22) | 141 (50.54) | ||||
allele | T | 182 (31.60) | 155 (27.78) | 1.98 | 0.160 | 0.960 |
C | 394 (68.40) | 403 (72.22) | ||||
EBF1 rs2946169 C/T | ||||||
genotype | CC | 165 (57.10) | 180 (64.52) | 4.78 | 0.092 | 0.552 |
CT | 103 (35.64) | 88 (31.54) | ||||
TT | 21 (7.26) | 11 (3.94) | ||||
allele | C | 433 (74.91) | 450 (80.65) | 5.38 | 0.020 | 0.120 |
T | 145 (25.09) | 108 (19.35) | ||||
TNF-α rs1800629 G/A | ||||||
genotype | GG | 208 (71.23) | 213 (75.80) | 7.68 | 0.104 | 0.624 |
GA | 70 (23.97) | 59 (21.00) | ||||
AA | 14 (4.80) | 9 (3.20) | ||||
allele | G | 486 (83.22) | 485 (86.47) | 2.10 | 0.148 | 0.888 |
A | 98 (16.78) | 77 (13.70) |
Bold denotes statistical significance. * Pearson chi-square test. ** Bonferroni correction. Genotype data were available for ASTN1 cases 289/292 (99.0%) and 277/281 (98.6%) controls; EBF1 cases 288/292 (98.6%) and 279/281 (93.3%) controls; and TNF-α cases 292/292 (100.0%) and 281/281 (100.0%) controls.