Table 1.
Baseline | 6-Month Follow-Up | ||||||
---|---|---|---|---|---|---|---|
N | Mean | SD | N | Mean | SD | p | |
SLTS-7 composite (Items 2–7) | 121 | 39.5 | 10.2 | 121 | 41.9 | 12.0 | 0.04 |
Satisfaction with | |||||||
|
121 | 6.8 | 2.0 | 121 | 7.1 | 1.9 | 0.100 |
|
121 | 5.1 | 2.2 | 121 | 5.9 | 2.0 | <0.001 |
|
121 | 6.9 | 2.2 | 121 | 7.0 | 2.3 | 0.624 |
|
121 | 7.2 | 2.2 | 121 | 7.2 | 2.2 | 0.675 |
|
121 | 6.8 | 2.2 | 121 | 7.1 | 2.1 | 0.168 |
|
121 | 7.0 | 2.2 | 121 | 7.7 | 2.0 | 0.003 |
|
121 | 6.5 | 2.2 | 121 | 7.1 | 2.5 | 0.035 |
Psycho-social well-being domain (Items 3–5) |
121 | 20.9 | 5.7 | 121 | 21.3 | 6.1 | 0.224 |
Treatment domain (Items 6–7) | 121 | 13.6 | 4.2 | 121 | 14.8 | 4.2 | 0.007 |
PDQ-8 Summary Index | 121 | 31.9 | 15.7 | 120 | 24.4 | 16.1 | <0.001 |
EQ-5D-3L TTO * | 119 | 0.8 | 0.2 | 120 | 0.8 | 0.2 | 0.001 |
EQ-VAS | 118 | 57.2 | 19.6 | 119 | 64.4 | 19.1 | 0.001 |
NMSS total | 121 | 56.3 | 31.1 | 120 | 39.1 | 25.2 | <0.001 |
HADS total | 120 | 10.5 | 6.3 | 121 | 8.9 | 6.2 | 0.003 |
UPDRS total | 120 | 24.0 | 10.7 | 113 | 18.0 | 9.2 | <0.001 |
Part I: cognition, behavior, mood | 121 | 1.9 | 1.7 | 121 | 1.6 | 1.3 | 0.281 |
Part II: activities of daily living | 121 | 12.5 | 5.9 | 121 | 9.7 | 5.4 | <0.001 |
Part III: motor examination | 120 | 24.0 | 10.7 | 113 | 18.0 | 9.2 | <0.001 |
Part IV: motor complications | 121 | 6.9 | 3.5 | 121 | 3.7 | 3.2 | <0.001 |
LEDD total | 121 | 1125.4 | 529.6 | 121 | 536.6 | 296.9 | <0.001 |
Significant results are highlighted in bold font. Within group changes from baseline to 6-month follow-up were analyzed with Wilcoxon signed-rank tests. Post-hoc, we explored the SLTS-7 items and composite scores. Abbreviations: EQ-5D-3L = European Quality of Life Questionnaire with 5 Dimensions and 3 Levels; HADS = Hospital Anxiety and Depression Scale; LEDD = Levodopa Equivalent Daily Dose; NMSS = Non-Motor Symptom Scale; N = Number; PDQ-8 = eight-item Parkinson’s Disease Questionnaire; SD = Standard Deviation; SLTS-7 = Satisfaction with Life and Treatment Scale-7; TTO = Time-Trade-Off; UPDRS = Unified Parkinson’s Disease Rating Scale; VAS = Visual Analogue Scale. * Adapted to Country according to EuroQol.