Table 1.
EUS description of SELs.
| Subepithelial Lesion | Layer of Origin | Echogenicity | Location in GI Tract | Malignant Potential |
|---|---|---|---|---|
| Lymphoma (5) |
2nd/3rd/4th | Hypoechoic | Anywhere in the GI tract | Yes |
| Lymphangioma (5) |
3rd | Anechoic, no Doppler signal, with internal septa | Small intestine | No |
| Schwannoma (8) |
4th | Hypoechoic, homogenous, sometimes with marginal halo | Stomach (body) | No |
| GIST (9) |
2nd/4th | Hypoechoic, hypervascular, heterogeneous with cystic space or echogenic foci | Stomach | Yes |
| Leiomyoma (11) |
2nd/4th | Hypoechoic, rarely multifocal fine margin |
Esophagus | No |
| Varices (11) |
3rd | Anechoic with Doppler signal | Esophagus | No |
| Neuroendocrine tumor (12) |
1st/2nd/3rd | Hypoechoic/hyperechoic | Stomach, duodenum, rectum | Yes |
| Lipoma (16) |
3rd | Hyperechoic, homogenous | Anywhere in the GI tract | No |
| Duplication cyst (17) |
3rd/external | Anechoic, no Doppler signal | Esophagus | Very Rarely |
| Heterotopic pancreas (19) |
3rd/4th | Hypoechoic, heterogenous, with cysts or ducts inside | Stomach (antrum) | Very rarely |
| Glomus tumor (38) |
3rd/4th | Hypo-hyperechoic, hypervascular with internal echo | Anywhere in the GI tract | Yes |