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. 2024 Sep 27;12(10):1962. doi: 10.3390/microorganisms12101962

Table 1.

Antifungal susceptibility testing of the two C. auris isolates (upper part) and the mutations detected (lower part). * N/A: data not available.

MIC Patient A Patient B CDC’s Tentative MIC
Breakpoints
Amphotericin B 2 R 4 R ≥2
Anidulafungin 0.12 S 0.12 S ≥4
Caspofungin 0.12 S 0.12 S ≥2
Fluconazole 128 R 256 R ≥32
Isavuconazole 0.06 N/A * 0.12 N/A N/A
Itraconazole 0.12 N/A 0.25 N/A N/A
Micafungin 0.12 S 0.12 S ≥4
Posaconazole 0.06 N/A 0.06 N/A N/A
Voriconazole 0.5 N/A 0.5 N/A N/A
Mutations
Gene Gene ID Substitution
CIS2 B9J08_01093 K74E
ERG4 B9J08_00711 M192I
SNQ2 B9J08_03375 K52N
STE6 B9J08_05399 K719N
ERG11 B9J08_03698 Y132F+
TAC1B B9J08_04780 A583S
FCY1 PIS48695.1 S70R+