Table 1.
Baseline characteristics of the cohort
| Variable | Cohort (n = 279) |
|---|---|
| Demographics and baseline characteristics of the cohort | |
| Age (IQR), years | 69 (57–80) |
| Male, n (%) | 119 (43) |
| White, n (%) | 253 (91) |
| BMI (IQR) | 30 (25–34) |
| History of HTN, n (%) | 213 (76) |
| History of DM, n (%) | 83 (70) |
| History of stroke, n (%) | 53 (19) |
| History of cardiac disease, n (%) | 98 (35) |
| History of CKD, n (%) | 37 (13) |
| Baseline mRS (IQR) | 0 (0–0) |
| PTA antithrombotics, n (%) | 95 (34) |
| Evaluation and stroke metrics | |
| Nighttime 7 p.m.–7 a.m., n (%) | 87 (31) |
| Initial GCS (IQR) | 15 (13–15) |
| Initial NIHSS (IQR) | 7 (4–13) |
| Initial SBP (IQR), mm Hg | 157 (136–173) |
| Initial glucose (IQR), mg/dL | 114 (99–149) |
| Last known well to treatment (IQR), min | 128 (91–180) |
| Door to needle time (IQR), min | 51 (39–69) |
| ASPECT score (IQR) | 10 (10–10) |
| Hyperdense MCA sign, n (%) | 30 (11) |
| M1 occlusion on CTA, n (%) | 36 (13) |
| tPA complications, n (%) | |
| Symptomatic ICH | 8 (3) |
| Systemic bleeding | 7 (2.5) |
| Allergy/angioedema | 3 (1) |
| Thrombectomy | 28 (10) |
| Posterior circulation stroke | 34 (12) |
| Outcome measures | |
| Median LOS (IQR) | 3 (2–5) |
| In-hospital mortality, n (%) | 19 (7) |
| Discharge home or inpatient rehab, n (%) | 233 (83) |
| mRS 0–2 at 30 days, n (%) | 185 (66) |
| mRS 5–6 at 30 days, n (%) | 39 (14) |