Table 2.

Uniquely detected proteins in orbital fat (in at least 40% of patients).

Protein ID	Protein Name	% of Patients	p-Value	Database	Pathways
Q16678	Cytochrome P450 1B1	90%	5.23 × 10−5	KEGG	Steroid hormone biosynthesis, tryptophan metabolism, metabolism of xenobiotics by Cytochrome P450, ovarian steroidogenesis, chemical carcinogenesis—DNA adducts, MicroRNAs in cancer, chemical carcinogenesis—receptor activation, chemical carcinogenesis—reactive oxygen species.
O94788	Retinal dehydrogenase 2	50%	9.82 × 10−3	KEGG	Metabolic pathways, retinol metabolism
P02812	Basic salivary proline-rich protein 2	40%	2.53 × 10−2	KEGG	Salivary secretion
Q13740	CD166 antigen	40%	2.53 × 10−2	KEGG	Cell adhesion molecules
P08582	Melanotransferrin	40%	2.53 × 10−2	PHAROS	Protein metabolism, post-translational protein modification, post-translational modification: synthesis of GPI-anchored proteins, post-translational protein phosphorylation, regulation of insulin-like growth factor transport and uptake by insulin-like growth factor binding proteins