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Germline stem cell (GSC) competition in the ovary. Mutation of bag of marbles (bam) in a female Drosophila GSC clone (orange) causes an accumulation of undifferentiated GSC-like cells (orange), which outcompete wild-type GSC neighbors (blue) for niche (green) access. Autophagy is required for bam-mutant germline cells’ competitive advantage; bam-mutant GSCs that have inhibited autophagy no longer outcompete wild-type GSCs. Escort cells are shown in gray. Created with BioRender.com.
