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. 2024 Oct 10;12(10):2050. doi: 10.3390/microorganisms12102050

Table 2.

Evaluation of diagnostic and therapeutic characteristics and modalities in patient management; md—mediana; IQR—interquartile range; HCC—hepatocellular carcinoma; RFA—radiofrequency ablation; TACE—trans-arterial chemoembolization.

Variable N = 216
HCV RNA quantitative testing, median (IQR) 523,500.0 (18,310.0–2,235,400.0)
Sustained virologic response, n (%) at post-treatment Week 4 212 (98.1)
at post-treatment Week 12 211 (97.7)
Hepatitis C genotype, n (%) 1a 79 (36.5)
1b 39 (18.1)
2 5 (2.3)
3 73 (33.8)
4 20 (9.3)
Antiviral therapy, n (%) Glecaprevir/pibrentasvir 118 (54.6)
Elbasvir/grazoprevir 30 (13.9)
Sofosbuvir/velpatasvir +/− ribavirin 68 (36.0)
Method of liver fibrosis assessment, n (%) Fibrosis-4 (FIB-4) index 61 (28.2)
Liver stiffness measurement 127 (58.8)
Liver biopsy 28 (13.0)
Fibrosis stage, n (%) F0/1 113 (52.3)
F2 34 (15.8)
F3 16 (7.4)
F4 53 (24,5)
Liver stiffness measurement F0/1, n (%) 74 (34.3)
F2, n (%) 21 (9.7)
F3, n (%) 6 (2.8)
F4, n (%) 17 (7.9)
Fibrosis stage kPa, md (IQR) 6.5 (5.0–9.2)
Steatosis S0, n (%) 69 (31.9)
Steatosis S1, n (%) 26 (12.0)
Steatosis S2/3, n (%) 19 (8.8)
Degree of steatosis dB/m, md (IQR) 215.6 (190.1–242.5)
Fibrosis-4 index, n (%) F0/1 34 (15.8)
F2/3 10 (4.6)
F3/4 26 (12.0)
Liver cirrhosis and Child–Pugh classification Total cirrhotic patients 50 (23.1)
Class A 39 (18.0)
Class B 10 (4.6)
Class C 1 (0.5)
Complications of liver cirrhosis Ascites, n (%) 12 (5.5)
Hepatic encephalopathy, n (%) 5 (2.3)
Portal hypertension, n (%) 22 (10.1)
Esophageal varices, n (%) 20 (9.3)
Hepatocellular carcinoma and treatment modalities, n (%) Total HCC patients 10 (4.2)
Surgical resection 5 (2.3)
RFA/TACE 3 (1.4)
Palliative care 2 (0.9)