Effects of GEG on claudin 3 gene expression levels in amygdala, frontal cortex, hippocampus, and colon of male rats (A) and female rats (B) and protein expression levels in colon of male and female rats (C). For gene expression, data are expressed as mean ± SEM and were analyzed by one-way ANOVA followed by Tukey’s test, n = 7–9 per group. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 for SNL-V vs. Sham-V group, and other groups vs. SNL-V group. For protein expression, data are expressed as mean ± SEM and were analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test, n = 7–9 per group. * p < 0.05 compared with Sham-V group. + p < 0.05, ++ p < 0.01 compared with SNL-V group.