Figure 2.
Dendrogram of betacoronavirus spike protein RBD sequences, arterivirus GP2 sequences and torovirus sequences constructed using MWHP PCDTW with Euclidean distance and UPGMA hierarchical clustering. ACE2-binding betacoronavirus sequences are highlighted in red, and non-ACE2-binding betacoronavirus sequences are highlighted in blue. Three Arterivirus GP2 sequences that are unique within this study, in that they cluster very closely with ACE2-binding betacoronavirus sequence, are labeled with blue text. This combined dendrogram underscores the similarity of the three arterivirus GP2 sequences to those of the ACE2-binding betacoronavirus sequences.