Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Representative working model. The aqueous extracts of S. tetrandra and its effective compound coclaurine can interfere with the interaction between transcription factor FOXG1 and the EFHD2 promoter, thereby reducing EFHD2 mRNA levels and its transcription. Consequently, these treatments attenuate the expression of EFHD2-related signaling molecules NOX4 and ABCC1, leading to decrease cisplatin efflux and ultimately sensitize NSCLC cells to cisplatin.
