Figure 3.

Experiment 1. Mice were fasted from 2 h before gavage to 5 h after gavage. (A) The average of each group’s blood glucose in mg/dL at each timepoint is shown. For the overall responses, compared to the control group (0 mg/kg), the treatment groups showed significant differences as follows: at 2.5 mg/kg p < 0.01; at 5.0 mg/kg p < 0.0001; at 7.5 mg/kg p < 0.0001. (B) The average of each group’s blood BHB in mM at each timepoint is shown. Significant difference from the control group as follows: at 2.5 mg/kg p < 0.001; at 5.0 mg/kg p < 0.0001; at 7.5 mg/kg p < 0.0001. (C) The average of each group’s glucose ketone index (GKI) at each timepoint is shown. Significant difference from the control group as follows: at 2.5 mg/kg p < 0.0001; at 5.0 mg/kg p < 0.0001; at 7.5 mg/kg p < 0.0001. (D) BHB C_max, the maximum BHB levels measured for each individual test subject are shown. For all line graphs representing data, horizontal bars indicate timepoints when treatment and control measurements are significantly different from each other (p < 0.05). For all column graphs, groups of data points with shared alphabetic symbols are not significantly different from each other.