Table 1.
Baseline Characteristics | Overall (n = 102 *) | Soubgroup A (n = 28 **) | Subgroup B (n = 73 **) | p-Value |
---|---|---|---|---|
Patient characteristics | ||||
Male, n (%) | 73 (71.6%) | 23 (82.1%) | 49 (67.1%) | 0.135 |
Age (years), median (IQR) | 57 (50–62) | 57 (46–62) | 57 (52–63) | 0.719 |
Weight (kg), median (IQR) | 90 (80–100) | 85 (80–100) | 80 (80–102) | 0.447 |
BMI (kg/m2), median (IQR) | 29 (26–35) | 28 (26–31) | 31 (27–35) | 0.017 |
SOFA at admission, median (IQR) | 8 (7–9) | 7.5 (6.25–8) | 8 (7–9) | 0.313 |
SOFA at ECMO start, median (IQR) | 8 (7–9) | 8 (7–9) | 8 (7–9.5) | 0.695 |
SAPS II at admission, median (IQR) | 42 (37–49) | 40 (33.5–47.75) | 42 (38–51) | 0.183 |
SAPS II at ECMO start, median (IQR) | 40 (34–46) | 38.5 (33–44) | 40 (35–48.5) | 0.495 |
ECMO duration (days), median (IQR) | 20 (11–31) | 14 (9–28) | 20 (12–31) | 0.545 |
ICU LOS (days), median (IQR) | 35 (22–57) | 36 (24–53) | 35 (20–58) | 0.776 |
ICU mortality, n (%) | 42 (41.2%) | 10 (35.7%) | 31 (42.5%) | 0.536 |
Nutrition Data of 2344 days | ||||
Daily calorie del. (% of requ.) overall, mean (Std.) | 73.7 (29.1) | 71.6 (26.0) | 74.4 (30.0) | 0.475 |
Daily calorie del. (% of requ.) from EN, mean (Std.) | 51.0 (34.6) | 56.2 (30.6) | 49.4 (35.6) | <0.001 |
Daily calorie del. (% of requ.) from PN, mean (Std.) | 14.2 (23.9) | 9.4 (19.4) | 15.7 (25.0) | <0.001 |
Daily calorie del. (% of requ.) from prop., mean (Std.) | 8.6 (7.7) | 6.0 (7.1) | 9.4 (7.7) | <0.001 |
Daily protein del. (g/kg BW/d) overall, mean (Std.) | 0.69 (0.35) | 0.70 (0.32) | 0.70 (0.36) | 0.037 |
Daily protein del. (g/kg BW/d) from EN, mean (Std.) | 0.49 (0.36) | 0.55 (0.33) | 0.47 (0.37) | <0.001 |
Daily protein del. (g/kg BW/d) from PN, mean (Std.) | 0.21 (0.36) | 0.15 (0.32) | 0.23 (0.37) | <0.001 |
GRV (mL/24 h), mean ± Std. | 127.8 (232.4) | 107.6 (224.5) | 134.5 (234.9) | 0.001 |
* Data from Schneeweiß-Gleixner et al. ** Exclusion of one patient due to his position (prone only) during his ECMO support. Bold p-values indicate statistically significant results. Abbreviations: BMI—body mass index; BW—body weight; d—day; del.—delivery; ECMO—extracorporeal membrane oxygenation; EN—enteral nutrition; g—gram; ICU—intensive care unit; IQR—interquartile range; kg—kilogram; LOS—length of stay; m2—square meters; n—number; PN—parenteral nutrition; prop.—propofol; requ.—requirements; SAPS II—Simplified Acute Physiology Score II; SOFA—sequential organ failure assessment score; Std.—standard deviation; %—percent.